ID3 anticorps (N-Term)

N° du produit ABIN2779573

Détail du produit anti-ID3 anticorps

Antigène: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Lapin, Cheval, Boeuf (Vache), Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ID3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MKALSPVRGC YEAVCCLSER SLAIARGRGK GPAAEEPLSL LDDMNHCYSR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ID3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ID3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 119 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ID3 (ABIN2779573)

Tsuchiya, Okaji, Tsuno, Sakurai, Tsuchiya, Kawai, Yazawa, Asakage, Yamada, Yoneyama, Kitayama, Osada, Watanabe, Tokunaga, Takahashi, Nagawa: "Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer." dans: Cancer science, Vol. 96, Issue 11, pp. 784-90, (2005) (PubMed).

Détails sur ID3

Antigène: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Autre désignation: ID3 (ID3 Produits)

Synonymes: anticorps HEIR-1, anticorps bHLHb25, anticorps Hlh462, anticorps Idb3, anticorps fa56g03, anticorps tdsubc_2g3, anticorps wu:fa56g03, anticorps ik:tdsubc_2g3, anticorps xx:tdsubc_2g3, anticorps XId3, anticorps XIdI, anticorps XIdIa, anticorps XIdIb, anticorps XIdx, anticorps heir-1, anticorps id3, anticorps xid3, anticorps xidia, anticorps ID3, anticorps XIdIIa, anticorps inhibitor of DNA binding 3, HLH protein, anticorps inhibitor of DNA binding 3, anticorps inhibitor of DNA binding 3, HLH protein L homeolog, anticorps inhibitor of DNA binding 3, HLH protein S homeolog, anticorps ID3, anticorps Id3, anticorps id3, anticorps id3.L, anticorps id3.S

Sujet: ID3 is a member of the ID family. The members of the family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM].
Alias Symbols: HEIR-1, bHLHb25
Protein Interaction Partner: UBC, TCF12, TCF3, TCF4, FAM74A1, ZNF626, ZNF408, RND1, PUF60, ZNF3, MLX, CNOT3, ID3, GNB2, FHL2, CSK, ATF3, CDK2, SMURF2, PRDM14, CBFA2T2, SAP30, IKBKG, E2F4, GATA4, NKX2-5, ID4, GTF2A1L, ELK4, ELK1, SREBF1, PAX5, MYF6, MYF5, MYOG, MYOD1, IFI16, HES1, RUN
Protein Size: 119

Poids moléculaire: 13 kDa

ID gène: 3399

NCBI Accession: NM_002167, NP_002158

UniProt: Q02535