HDAC2 anticorps (C-Term)

N° du produit ABIN2779752

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC2 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Chien, Cheval, Porc et Saccharomyces cerevisiae.

Aperçu rapide pour HDAC2 anticorps (C-Term) (ABIN2779752)

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Chien, Cheval, Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HDAC2 anticorps

Épitope: C-Term

Séquence: EEFSDSEDEG EGGRRNVADH KKGAKKARIE EDKKETEDKK TDVKEEDKSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against HDAC2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 488 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HDAC2

Antigène: HDAC2 (Histone Deacetylase 2 (HDAC2))

Autre désignation: HDAC2

Sujet: Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
Alias Symbols: HD2, RPD3, YAF1
Protein Interaction Partner: BRCA1, SUMO1, UBC, SMAD7, SMAD2, MXD1, NCOR2, SUMO2, SFPQ, KDM5A, HDAC1, DDB1, CUL4B, CHFR, KDM1A, KDM5B, NFE2L2, PRDM6, DNMT3B, DNMT1, NACC2, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, PRDM1, EED, RNF2, SP1, CHD4, CHD3, ACTL6A, C16orf87, HMG20A, HMG20B, C
Protein Size: 488

Poids moléculaire: 55 kDa

ID gène: 3066

NCBI Accession: NM_001527, NP_001518

UniProt: Q92769

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2