TAF1A
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Machida, Takeda, Yokono, Ikemune, Taniguchi, Kiyosawa, Takemasa: "Reduction of ribosome biogenesis with activation of the mTOR pathway in denervated atrophic muscle." dans: Journal of cellular physiology, Vol. 227, Issue 4, pp. 1569-76, (2012) (PubMed).
Antigène
TAF1A
(TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A, 48kDa (TAF1A))
anticorps TAFI48, anticorps mTAFI48, anticorps MGC:17061, anticorps RAFI48, anticorps SL1, anticorps TATA-box binding protein associated factor, RNA polymerase I, A, anticorps TATA-box binding protein associated factor, RNA polymerase I subunit A, anticorps Taf1a, anticorps TAF1A
Sujet
Taf1a is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Alias Symbols: - Protein Size: 453