SMAD4 anticorps (N-Term)

N° du produit ABIN2780673

Cet anticorps Lapin Polyclonal détecte spécifiquement SMAD4 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Chévre, Cobaye, Cheval et Mouton.

Aperçu rapide pour SMAD4 anticorps (N-Term) (ABIN2780673)

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Chévre, Cobaye, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SMAD4 anticorps

Épitope: N-Term

Séquence: MDNMSITNTP TSNDACLSIV HSLMCHRQGG ESETFAKRAI ESLVKKLKEK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SMAD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 552 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMAD4

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation: SMAD4

Sujet: SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantl
Alias Symbols: DPC4, JIP, MADH4, MYHRS
Protein Interaction Partner: RASSF5, LMO4, SMAD3, SMAD2, SKIL, UBC, NEDD8, SUMO1, SMURF2, SMURF1, TRIM33, CRYAB, COPS5, NLK, OTUB1, SMAD9, UBE2I, FHL3, FHL2, FHL1, CSNK1D, TGFB1I1, SMAD1, NCOR1, SKI, KLF5, IRF7, IRF3, ZNF521, ZNF423, SOX12, SNRNP70, RPL28, RFX1, RELA, RALA, PSMD11, P
Protein Size: 552

Poids moléculaire: 60 kDa

ID gène: 4089

NCBI Accession: NM_005359, NP_005350

UniProt: Q13485

Pathways: Cycle Cellulaire, Chromatin Binding, Autophagy