Coronin 1a anticorps (C-Term)

N° du produit ABIN2780827

Détail du produit anti-Coronin 1a anticorps

Antigène: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coronin 1a est non-conjugé

Application: Western Blotting (WB)

Séquence: ELRVNRGLDT GRRRAAPEAS GTPSSDAVSR LEEEMRKLQA TVQELQKRLD

Homologie: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 90%, Rabbit: 79%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against CORO1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CORO1A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 461 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Coronin 1a

Antigène: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Autre désignation: CORO1A (CORO1A Produits)

Synonymes: anticorps CORO1A, anticorps cor1a, anticorps Clabp, anticorps Lmb3, anticorps TACO, anticorps p57, anticorps CLABP, anticorps CLIPINA, anticorps HCORO1, anticorps fj83g12, anticorps wu:fj83g12, anticorps zgc:63766, anticorps coronin 1A, anticorps Coronin-1A, anticorps coronin, actin binding protein 1A, anticorps coronin, actin binding protein, 1A, anticorps CORO1A, anticorps cor1a, anticorps Coro1a, anticorps coro1a

Sujet: CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages
Alias Symbols: p57, TACO, CLABP, HCORO1, CLIPINA
Protein Interaction Partner: FSD2, GOLGA2, UBC, YTHDC1, SPATA20, POT1, TAB1, GIT2, POLR1C, STAT3, SMARCD1, MAGOH, SMAD3, LMO2, FHL3, FMNL1, NCF4, THBS1, ACTB, DKK1, UBE2G2,
Protein Size: 461

Poids moléculaire: 51 kDa

ID gène: 11151

NCBI Accession: NM_007074, NP_009005

UniProt: Q2YD73

Pathways: Regulation of Actin Filament Polymerization