MESP1 anticorps (N-Term)

N° du produit ABIN405225

Détail du produit anti-MESP1 anticorps

Antigène: MESP1 (Mesoderm Posterior 1 (MESP1))

Épitope: N-Term

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MESP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SLVSSPDSWG STPADSPVAS PARPGTLRDP RAPSVGRRGA RSSRLGSGQR

Homologie: Dog: 85%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MESP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MESP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 268 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MESP1 (ABIN405225)

Tan, Han, Gu, Chen, Wang, Ma, Wu, Feng, Zhang, Wang, Hu, Li, Hao, Zhou: "Generation of clinical-grade functional cardiomyocytes from human embryonic stem cells in chemically defined conditions." dans: Journal of tissue engineering and regenerative medicine, (2016) (PubMed).

Hu, Wang, Jiao, Liu, Zhao, Zhou, Zhang, Forde, Wang, Wang, Baylink, Zhang, Gao, Yang, Chen, Ma: "Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration." dans: Biomaterials, Vol. 73, pp. 51-9, (2015) (PubMed).

Cao, Liang, Huang, Wang, Chen, Chen, Yang: "Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions." dans: Cell research, Vol. 23, Issue 9, pp. 1119-32, (2013) (PubMed).

Blin, Nury, Stefanovic, Neri, Guillevic, Brinon, Bellamy, Rücker-Martin, Barbry, Bel, Bruneval, Cowan, Pouly, Mitalipov, Gouadon, Binder, Hagège, Desnos, Renaud, Menasché, Pucéat: "A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates." dans: The Journal of clinical investigation, Vol. 120, Issue 4, pp. 1125-39, (2010) (PubMed).

Détails sur MESP1

Antigène: MESP1 (Mesoderm Posterior 1 (MESP1))

Autre désignation: MESP1 (MESP1 Produits)

Synonymes: anticorps bHLHc5, anticorps mesp, anticorps mesp1, anticorps mespa, anticorps CMESO-1, anticorps CMESO2, anticorps MESP1, anticorps mesoderm posterior 1, anticorps mesoderm posterior bHLH transcription factor 1, anticorps mesoderm posterior 1 homolog (mouse), anticorps mesoderm posterior homolog B, anticorps mesoderm posterior homolog B L homeolog, anticorps Mesp1, anticorps MESP1, anticorps mesp1, anticorps mespb, anticorps mespb.L

Sujet: MESP1 is a transcription factor. MESP1 plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. MESP1 defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
Alias Symbols: MGC10676, bHLHc5
Protein Size: 268

Poids moléculaire: 28 kDa

ID gène: 55897

NCBI Accession: NM_018670, NP_061140

UniProt: Q9BRJ9

Pathways: Regulation of Muscle Cell Differentiation