NSMCE1 anticorps (Middle Region)

N° du produit ABIN2781252

Détail du produit anti-NSMCE1 anticorps

Antigène: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Cobaye, Lapin, Boeuf (Vache), Chévre, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSMCE1 est non-conjugé

Application: Western Blotting (WB)

Séquence: KKEAEQVLQK FVQNKWLIEK EGEFTLHGRA ILEMEQYIRE TYPDAVKICN

Homologie: Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NSMCE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NSMCE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 266 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NSMCE1

Antigène: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Autre désignation: NSMCE1 (NSMCE1 Produits)

Synonymes: anticorps zgc:92777, anticorps NSMCE1, anticorps NSE1, anticorps 2510027N19Rik, anticorps RGD1307760, anticorps NSE1 homolog, SMC5-SMC6 complex component, anticorps NSE1 homolog, SMC5-SMC6 complex component L homeolog, anticorps nsmce1, anticorps NSMCE1, anticorps nsmce1.L, anticorps Nsmce1

Sujet: NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
Alias Symbols: NSE1
Protein Interaction Partner: UBC, EID3, SMC6, NDNL2, Ube2k, UBE2D2, NSMCE2, NSMCE1, NSMCE4A, SMC5, SUMO2, MAGEF1,
Protein Size: 266

Poids moléculaire: 31 kDa

ID gène: 197370

NCBI Accession: NM_145080, NP_659547

UniProt: Q8WV22

Pathways: Positive Regulation of Response to DNA Damage Stimulus