SLC5A5 anticorps (Middle Region)

N° du produit ABIN405589

Détail du produit anti-SLC5A5 anticorps

Antigène: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC5A5 est non-conjugé

Application: Western Blotting (WB)

Séquence: PSEQTMRVLP SSAARCVALS VNASGLLDPA LLPANDSSRA PSSGMDASRP

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SLC5A5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SLC5A5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 643 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC5A5 (ABIN405589)

Liu, Lunsford, Tong, Ashitate, Gibbs, Yu, Choi, Henske, Frangioni: "Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex." dans: PLoS ONE, Vol. 7, Issue 6, pp. e38589, (2012) (PubMed).

Détails sur SLC5A5

Antigène: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Autre désignation: SLC5A5 (SLC5A5 Produits)

Synonymes: anticorps Na(+)/I(-) cotransporter, anticorps Na(+)/I(-) symporter, anticorps Nis, anticorps solute carrier family 5 member 5, anticorps Slc5a5

Sujet: The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NIS, TDH1
Protein Interaction Partner: ERBB2IP, SLC5A5,
Protein Size: 643

Poids moléculaire: 69 kDa

ID gène: 6528

NCBI Accession: NM_000453, NP_000444

UniProt: Q92911