PTGIS anticorps (Middle Region)

N° du produit ABIN2781839

Détail du produit anti-PTGIS anticorps

Antigène: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGIS est non-conjugé

Application: Western Blotting (WB)

Séquence: EIYTDPEVFK YNRFLNPDGS EKKDFYKDGK RLKNYNMPWG AGHNHCLGRS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against PTGIS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PTGIS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 500 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTGIS

Antigène: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Autre désignation: PTGIS (PTGIS Produits)

Synonymes: anticorps CYP8, anticorps CYP8A1, anticorps PGIS, anticorps PTGI, anticorps Cyp8, anticorps Cyp8a1, anticorps Pgis, anticorps ptgisl, anticorps PTGIS, anticorps prostaglandin I2 synthase, anticorps prostaglandin I2 (prostacyclin) synthase, anticorps prostacyclin synthase, anticorps PTGIS, anticorps Ptgis, anticorps ptgis, anticorps VDBG_06319

Sujet: PTGIS is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CYP8, CYP8A1, MGC126858, MGC126860, PGIS, PTGI
Protein Interaction Partner: CAV1, PTGS2, PTGS1, APP,
Protein Size: 500

Poids moléculaire: 57 kDa

ID gène: 5740

NCBI Accession: NM_000961, NP_000952

UniProt: Q16647