HBEGF anticorps (N-Term)

N° du produit ABIN2782149

L’anticorps anti-HBEGF Polyclonal Lapin est utilisé pour la détection de HBEGF dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cobaye et Lapin. Il a été validé pour WB.

Aperçu rapide pour HBEGF anticorps (N-Term) (ABIN2782149)

Antigène: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HBEGF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HBEGF anticorps

Épitope: N-Term

Fonction: HBEGF Antibody - N-terminal region

Séquence: FLAAVLSALV TGESLERLRR GLAAGTSNPD PPTVSTDQLL PLGGGRDRKV

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HBEGF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HBEGF

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45201-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HBEGF

Antigène: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Autre désignation: HBEGF

Sujet:

Background Information: HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Gene Name: heparin-binding EGF-like growth factor

Alternative Symbols: DTR, DTS, DTSF, HEGFL

Protein Name: Proheparin-binding EGF-like growth factor

Poids moléculaire: 22kDa

ID gène: 1839

NCBI Accession: NP_001936

UniProt: Q99075

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway