TNFRSF21 anticorps (N-Term)

N° du produit ABIN2782812

Détail du produit anti-TNFRSF21 anticorps

Antigène: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF21 est non-conjugé

Application: Western Blotting (WB)

Séquence: TTTAQPEQKA SNLIGTYRHV DRATGQVLTC DKCPAGTYVS EHCTNTSLRV

Homologie: Cow: 92%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 91%, Rabbit: 93%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against TNFRSF21. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF21

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 655 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNFRSF21

Antigène: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Autre désignation: TNFRSF21 (TNFRSF21 Produits)

Synonymes: anticorps TNFRSF21, anticorps tnfrsf21, anticorps MGC146356, anticorps BM-018, anticorps CD358, anticorps DR6, anticorps AA959878, anticorps R74815, anticorps TR7, anticorps dr6, anticorps im:6795346, anticorps wu:fa55e01, anticorps wu:fb02e11, anticorps wu:fc29a09, anticorps wu:fi27h08, anticorps TNF receptor superfamily member 21, anticorps tumor necrosis factor receptor superfamily member 21, anticorps tumor necrosis factor receptor superfamily, member 21, anticorps TNFRSF21, anticorps tnfrsf21, anticorps Tnfrsf21

Sujet: TNFRSF21 is a member of the TNF-receptor superfamily. This receptor has been shown to activate!!NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of!!TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Alias Symbols: BM-018, DR6, MGC31965, CD358
Protein Interaction Partner: NSD1, CLIP3, ELAVL1, WASH2P, MATR3, STX11, TRADD,
Protein Size: 655

Poids moléculaire: 68 kDa

ID gène: 27242

NCBI Accession: NM_014452, NP_055267

UniProt: O75509

Pathways: Regulation of Lipid Metabolism by PPARalpha