PYHIN1 anticorps (N-Term)
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- Antigène Voir toutes PYHIN1 Anticorps
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PYHIN1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KMKEEYDKIQ IADLMEEKFP GDAGLGKLIE FFKEIPTLGD LAETLKREKL
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PYHIN1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PYHIN1
- Top Product
- Discover our top product PYHIN1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 452 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- Autre désignation
- PYHIN1 (PYHIN1 Produits)
- Synonymes
- anticorps IFIX, anticorps RP11-520H16.1, anticorps 4930422C14, anticorps AI447904, anticorps Ifi209, anticorps Ifix, anticorps pyrin and HIN domain family member 1, anticorps interferon activated gene 209, anticorps PYHIN1, anticorps Ifi209
- Sujet
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PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Interaction Partner: MDM2,
Protein Size: 452 - Poids moléculaire
- 51 kDa
- ID gène
- 149628
- NCBI Accession
- NM_198930, NP_945148
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