Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

GRK2 anticorps (C-Term)

ADRBK1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784715
  • Antigène Voir toutes GRK2 (ADRBK1) Anticorps
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Épitope
    • 16
    • 11
    • 10
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 98
    • 77
    • 56
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye
    Hôte
    • 92
    • 8
    • 2
    • 2
    Lapin
    Clonalité
    • 87
    • 17
    Polyclonal
    Conjugué
    • 58
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRK2 est non-conjugé
    Application
    • 56
    • 45
    • 31
    • 17
    • 14
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    ILQCDSDPEL VQWKKELRDA YREAQQLVQR VPKMKNKPRS PVVELSKVPL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ADRBK1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human ADRBK1
    Top Product
    Discover our top product ADRBK1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 689 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Autre désignation
    ADRBK1 (ADRBK1 Produits)
    Synonymes
    anticorps Adrbk-1, anticorps Bark-1, anticorps GRK2, anticorps betaARK1, anticorps BARK1, anticorps BETA-ARK1, anticorps GRK-2, anticorps Grk2, anticorps beta-adrenergic receptor kinase 1, anticorps G protein-coupled receptor kinase 2, anticorps Tsp_00497, anticorps grk2, anticorps Grk2, anticorps GRK2
    Sujet
    The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
    Alias Symbols: BARK1, BETA-ARK1, FLJ16718, GRK2
    Protein Interaction Partner: UBC, SUMO1, NEDD8, Rapgef3, GNAQ, FBXO25, ADRBK2, ACACA, HSP90AB1, HSP90AA1, GIT1, RASGRF1, MDM2, EPHA2, PEBP1, ADRB2, SNCA, GRM1, GNB1, KCNIP3, ARRB1, HDAC6, Nedd4, CSNK2B, PDGFRB, TPM2, GIT2, PDE6G, CCR4, AKAP12, PDCL, NCS1, MAPK3, PRKACA, CCR5, PIK3CG,
    Protein Size: 689
    Poids moléculaire
    79 kDa
    ID gène
    156
    NCBI Accession
    NM_001619, NP_001610
    UniProt
    P25098
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
Vous êtes ici:
Support technique