Peroxiredoxin 3 anticorps (N-Term)

N° du produit ABIN2784892

Détail du produit anti-Peroxiredoxin 3 anticorps

Antigène: Peroxiredoxin 3 (PRDX3)

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: AIPWGISATA ALRPAACGRT SLTNLLCSGS SQAPYFKGTA VVNGEFKDLS

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRDX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 238 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Peroxiredoxin 3

Antigène: Peroxiredoxin 3 (PRDX3)

Autre désignation: PRDX3 (PRDX3 Produits)

Synonymes: anticorps cb718, anticorps wu:fk49e09, anticorps zgc:110282, anticorps zgc:112512, anticorps MGC83969, anticorps PRDX3, anticorps AOP-1, anticorps AOP1, anticorps HBC189, anticorps MER5, anticorps PRO1748, anticorps SP-22, anticorps prx-III, anticorps AW822249, anticorps Aop1, anticorps D0Tohi1, anticorps Ef2l, anticorps Mer5, anticorps Prx3, anticorps SP22, anticorps TDXM, anticorps MTAP, anticorps peroxiredoxin 3, anticorps peroxiredoxin 3 S homeolog, anticorps peroxiredoxin PRX3, anticorps prdx3, anticorps PRDX3, anticorps prdx3.S, anticorps PRX3, anticorps Prdx3

Sujet: PRDX3 is a protein with antioxidant function and is localized in the mitochondrion. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: AOP-1, AOP1, MER5, MGC104387, MGC24293, PRO1748, SP-22, HBC189, prx-III
Protein Interaction Partner: GORASP2, SUMO1, NEDD8, MDM2, ARMCX3, NUSAP1, LNPEP, HNRNPD, NEK6, CDK2, UBC, TNFRSF1A, ITGA4, FN1, RPS6KC1, PRDX3, PRDX4, VCAM1, RNASET2, PSME1, PFKL, SPEN, UBQLN4, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, SUMO4, MAPK3, NLRX1, HDAC5, UCHL5, H2AFX, T
Protein Size: 238

Poids moléculaire: 26 kDa

ID gène: 10935

NCBI Accession: NM_014098, NP_054817

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process