SQSTM1 anticorps (Middle Region)

N° du produit ABIN2785619

Cet anticorps Lapin Polyclonal détecte spécifiquement SQSTM1 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Cheval, Chien, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour SQSTM1 anticorps (Middle Region) (ABIN2785619)

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Cheval, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SQSTM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SQSTM1 anticorps

Épitope: Middle Region

Séquence: EEQMESDNCS GGDDDWTHLS SKEVDPSTGE LQSLQMPESE GPSSLDPSQE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SQSTM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SQSTM1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 440 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SQSTM1

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Autre désignation: SQSTM1

Sujet: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to m
Alias Symbols: A170, OSIL, PDB3, ZIP3, p60, p62, p62B
Protein Interaction Partner: HTT, BCL2, ATXN3, MAP1LC3A, tat, GABARAPL1, GABARAPL2, KEAP1, SQSTM1, UBC, TP53, TRIM63, TRIM55, MAP1LC3B, TOLLIP, ULK1, GABARAP, OPTN, SESN2, SUMO3, NBR1, EPAS1, EGLN3, CFTR, DCP2, MGRN1, NEDD8, EDEM1, LGALS3, IKBKG, TNK2, DVL2, FLNB, PSMD12, PSMD10, PSM
Protein Size: 440

Poids moléculaire: 48 kDa

ID gène: 8878

NCBI Accession: NM_003900, NP_003891

UniProt: Q13501

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy