JAK3 anticorps (N-Term)

N° du produit ABIN2785644

Détail du produit anti-JAK3 anticorps

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK3 est non-conjugé

Application: Western Blotting (WB)

Séquence: APPSEETPLI PQRSCSLLST EAGALHVLLP ARGPGPPQRL SFSFGDHLAE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human JAK3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur JAK3

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Autre désignation: JAK3 (JAK3 Produits)

Synonymes: anticorps JAK-3, anticorps JAK3_HUMAN, anticorps JAKL, anticorps L-JAK, anticorps LJAK, anticorps fae, anticorps wil, anticorps RATJAK3, anticorps JAK, anticorps Janus kinase 3, anticorps JAK3, anticorps Jak3

Sujet: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Alias Symbols: JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
Protein Size: 619

Poids moléculaire: 68 kDa

ID gène: 3718

NCBI Accession: NM_000215, NP_000206

UniProt: Q8N1E8

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response