PHLDA1 anticorps (Middle Region)

N° du produit ABIN2785897

Détail du produit anti-PHLDA1 anticorps

Antigène: PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Cobaye, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHLDA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PAVASLEPPV KLKELHFSNM KTVDCVERKG KYMYFTVVMA EGKEIDFRCP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PHLDA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PHLDA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 401 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PHLDA1 (ABIN2785897)

Tsuda, Davis, Argani, Shukla, McGill, Nagai, Saito, Laé, Fisher, Ladanyi: "TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition." dans: Cancer research, Vol. 67, Issue 3, pp. 919-29, (2007) (PubMed).

Détails sur PHLDA1

Antigène: PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))

Autre désignation: PHLDA1 (PHLDA1 Produits)

Synonymes: anticorps DT1P1B11, anticorps PHRIP, anticorps TDAG51, anticorps Tdag, anticorps pleckstrin homology like domain family A member 1, anticorps pleckstrin homology like domain, family A, member 1, anticorps pleckstrin homology-like domain, family A, member 1, anticorps pleckstrin homology-like domain, family A, member 1 L homeolog, anticorps PHLDA1, anticorps Phlda1, anticorps phlda1.L

Sujet: PHLDA1 is an evolutionarily conserved proline-histidine rich nuclear protein. It may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.
Alias Symbols: DT1P1B11, MGC131738, PHRIP, TDAG51
Protein Interaction Partner: UBC, SUMO1, MDFI, EGFR, APP, DNAJB1, HSPB1, HSPA4, ELAVL1, KRTAP4-12, RPL14, PLSCR1, HSPA4L, EIF3D, PABPC4,
Protein Size: 401

Poids moléculaire: 45 kDa

ID gène: 22822

NCBI Accession: NM_007350, NP_031376

UniProt: Q8WV24