PPP2R2D anticorps (C-Term)

N° du produit ABIN2786544

Détail du produit anti-PPP2R2D anticorps

Antigène: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R2D est non-conjugé

Application: Western Blotting (WB)

Séquence: RRDVTLEASR ENSKPRASLK PRKVCTGGKR KKDEISVDSL DFNKKILHTA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Ppp2r2d. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 453 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PPP2R2D

Antigène: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Autre désignation: Ppp2r2d (PPP2R2D Produits)

Synonymes: anticorps 1300017E19Rik, anticorps D7Ertd753e, anticorps MDS026, anticorps protein phosphatase 2, regulatory subunit B, delta, anticorps protein phosphatase 2 regulatory subunit Bdelta, anticorps protein phosphatase 2 regulatory subunit B, delta S homeolog, anticorps Ppp2r2d, anticorps PPP2R2D, anticorps ppp2r2d.S

Sujet: Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
Alias Symbols: 1300017E19Rik, D7Ertd753e, MDS026
Protein Interaction Partner: Supt5, SMURF1, SMAD3, SMAD2,
Protein Size: 453

Poids moléculaire: 50 kDa

ID gène: 52432

NCBI Accession: NM_026391, NP_080667

UniProt: Q925E7