RAD51 Homolog B anticorps (Middle Region)

N° du produit ABIN2787357

Cet anticorps anti-RAD51 Homolog B est un anticorps Lapin Polyclonal détectant RAD51 Homolog B dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin et Cheval.

Aperçu rapide pour RAD51 Homolog B anticorps (Middle Region) (ABIN2787357)

Antigène: RAD51 Homolog B (Rad51B)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 Homolog B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAD51 Homolog B anticorps

Épitope: Middle Region

Séquence: TESAFSAERL VEIAESRFPR YFNTEEKLLL TSSKVHLYRE LTCDEVLQRI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RAD51L1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RAD51L1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 350 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAD51 Homolog B

Antigène: RAD51 Homolog B (Rad51B)

Autre désignation: RAD51L1

Sujet: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC34245, R51H2, RAD51B, REC2, hREC2, RAD51L1
Protein Interaction Partner: FAM9B, SWSAP1, UBC, HIST1H2BG, HIST2H4A, RAD51D, HIST1H3A, RAD51C, H1F0, XRCC2, RAD51, HIST1H1A, HIST3H2BB, HIST3H3, HIST4H4,
Protein Size: 350

Poids moléculaire: 38 kDa

ID gène: 5890

NCBI Accession: NM_133510, NP_598194

Pathways: Réparation de l'ADN