TCF7L1 anticorps (N-Term)

N° du produit ABIN2787453

Cet anticorps Lapin Polyclonal détecte spécifiquement TCF7L1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Lapin.

Aperçu rapide pour TCF7L1 anticorps (N-Term) (ABIN2787453)

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF7L1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TCF7L1 anticorps

Épitope: N-Term

Fonction: TCF7L1 Antibody - N-terminal region

Séquence: ESENQSSSSD SEAERRPQPV RDTFQKPRDY FAEVRRPQDS AFFKGPPYPG

Homologie: Cow: 86%, Dog: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57917-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TCF7L1

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Autre désignation: TCF7L1

Sujet:

Background Information: TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.

Gene Name: Transcription factor 7-like 1 (T-cell specific, HMG-box)

Alternative Symbols: TCF3, TCF-3

Protein Name: Transcription factor 7-like 1

Poids moléculaire: 63kDa

ID gène: 83439

NCBI Accession: NP_112573

UniProt: Q9HCS4

Pathways: Signalisation WNT, Stem Cell Maintenance