TCF7L1 anticorps (N-Term)

N° du produit ABIN1881874

Détail du produit anti-TCF7L1 anticorps

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Épitope: AA 70-98, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF7L1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TCF7L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human TCF7L1.

Clone: RB43616

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur TCF7L1

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Autre désignation: TCF7L1 (TCF7L1 Produits)

Synonymes: anticorps TCF-3, anticorps TCF3, anticorps Tcf-3, anticorps Tcf3, anticorps bHLHb21, anticorps tcf3c, anticorps tcf3d, anticorps xtcf3, anticorps XTCF-3, anticorps tcf7l1, anticorps tcf3b, anticorps TCF-3-A, anticorps tcf-3, anticorps tcf3, anticorps tcf3a, anticorps zTcf-3, anticorps transcription factor 7 like 1, anticorps transcription factor 7 like 1 (T cell specific, HMG box), anticorps transcription factor 7 like 1 L homeolog, anticorps transcription factor 7 like 1 S homeolog, anticorps transcription factor 7 like 1b, anticorps transcription factor 7 like 1a, anticorps TCF7L1, anticorps Tcf7l1, anticorps tcf7l1.L, anticorps tcf7l1.S, anticorps tcf7l1b, anticorps tcf7l1a

Sujet: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Poids moléculaire: 62631

NCBI Accession: NP_112573

UniProt: Q9HCS4

Pathways: Signalisation WNT, Stem Cell Maintenance