Calpain S1 anticorps (Middle Region)

N° du produit ABIN2787678

Cité dans 1 publication. Cet anticorps anti-Calpain S1 Polyclonal Lapin (ABIN2787678) détecte spécifiquement Calpain S1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Porc, Chien, Cobaye, Cheval et Mouton.

Aperçu rapide pour Calpain S1 anticorps (Middle Region) (ABIN2787678)

Antigène: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Porc, Chien, Cobaye, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpain S1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Calpain S1 anticorps

Épitope: Middle Region

Fonction: CAPNS1 Antibody - middle region

Séquence: RRYSDESGNM DFDNFISCLV RLDAMFRAFK SLDKDGTGQI QVNIQEWLQL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CAPNS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58434-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Calpain S1 (ABIN2787678)

Kulkarni, Liu, Qi, Zhu, Klinke, Liu: "Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis." dans: The Analyst, Vol. 138, Issue 22, pp. 6986-96, (2013) (PubMed).

Détails sur Calpain S1

Antigène: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Autre désignation: CAPNS1

Sujet:

Targeted Subunit: 1

Background Information: Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Gene Name: Calpain, small subunit 1

Alternative Symbols: CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4

Protein Name: Calpain small subunit 1

Poids moléculaire: 29kDa

ID gène: 826

NCBI Accession: NP_001003962

UniProt: P04632

Pathways: Apoptose