LKB1 anticorps (C-Term)
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- Antigène Voir toutes LKB1 (STK11) Anticorps
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Cheval, Cobaye, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LKB1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- EAPVPIPPSP DTKDRWRSMT VVPYLEDLHG ADEDEDLFDI EDDIIYTQDF
- Homologie
- Cow: 79%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against STK11. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human STK11
- Top Product
- Discover our top product STK11 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 433 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
- Autre désignation
- STK11 (STK11 Produits)
- Synonymes
- anticorps pjs, anticorps LKB1, anticorps XEEK1, anticorps Stk11, anticorps PJS, anticorps hLKB1, anticorps AA408040, anticorps Lkb1, anticorps Par-4, anticorps R75140, anticorps mLKB1, anticorps wu:fj61a05, anticorps zgc:110180, anticorps xeek1, anticorps serine/threonine kinase 11, anticorps polarization-related protein LKB1, anticorps serine/threonine kinase 11 L homeolog, anticorps STK11, anticorps stk11, anticorps LOC662493, anticorps Stk11, anticorps stk11.L
- Sujet
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STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Alias Symbols: LKB1, PJS, hLKB1
Protein Interaction Partner: SPDEF, SIRT1, PRKAA1, ETV4, CDC37, HSP90AA1, TP63, Eif2b1, Ap2m1, SNRK, APP, TNIP2, SIK1, STRADA, STUB1, UBE2D2, MARK2, GSK3B, STRADB, CAB39, KIF23, USP11, SMARCC1, SMARCA4, LIMS1, HSPA1A, FKBP5, RPAP3, MARK4, UBC, CAB39L, WDR48, RPS6KB1, MOB4, MARK1, RPS
Protein Size: 433 - Poids moléculaire
- 49 kDa
- ID gène
- 6794
- NCBI Accession
- NM_000455, NP_000446
- UniProt
- Q15831
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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