TNFSF4 anticorps (Middle Region)

N° du produit ABIN2787931

Détail du produit anti-TNFSF4 anticorps

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF4 est non-conjugé

Application: Western Blotting (WB)

Séquence: QEVNISLHYQ KDEEPLFQLK KVRSVNSLMV ASLTYKDKVY LNVTTDNTSL

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNFSF4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TNFSF4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 183 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNFSF4

Antigène: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Autre désignation: TNFSF4 (TNFSF4 Produits)

Synonymes: anticorps TNFSF4, anticorps OX40L, anticorps TNFRSF4, anticorps CD134L, anticorps CD252, anticorps GP34, anticorps OX-40L, anticorps OX4OL, anticorps TXGP1, anticorps Ath-1, anticorps Ath1, anticorps Ox40l, anticorps Txgp1l, anticorps gp34, anticorps TNF superfamily member 4, anticorps tumor necrosis factor (ligand) superfamily, member 4, anticorps TNFSF4, anticorps Tnfsf4

Sujet: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Alias Symbols: CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
Protein Interaction Partner: TRAF2, TNFRSF4,
Protein Size: 183

Poids moléculaire: 21 kDa

ID gène: 7292

NCBI Accession: NM_003326, NP_003317

UniProt: P23510

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints