Angiotensin II Type 2 Receptor anticorps (N-Term)

N° du produit ABIN2788290

Détail du produit anti-Angiotensin II Type 2 Receptor anticorps

Antigène: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin II Type 2 Receptor est non-conjugé

Application: Western Blotting (WB)

Séquence: LHFGLVNISG NNESTLNCSQ KPSDKHLDAI PILYYIIFVI GFLVNIVVVT

Homologie: Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against AGTR2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AGTR2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 363 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Angiotensin II Type 2 Receptor

Antigène: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Autre désignation: AGTR2 (AGTR2 Produits)

Synonymes: anticorps AT2, anticorps ATGR2, anticorps MRX88, anticorps AI316812, anticorps AW107640, anticorps AT2-R, anticorps AT2R, anticorps AT₂R, anticorps at2, anticorps zgc:113016, anticorps AGTR2, anticorps angiotensin II receptor type 2, anticorps angiotensin II receptor, type 2, anticorps AGTR2, anticorps Agtr2, anticorps agtr2

Sujet: The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
Alias Symbols: AT2, ATGR2, MRX88
Protein Interaction Partner: ERBB2IP, TIMP3, SNTA1, ZBTB16, MTUS1, PIK3CB, ERBB3, GNAI3, GNAI2, ACE, AGT, AGTRAP,
Protein Size: 363

Poids moléculaire: 41 kDa

ID gène: 186

NCBI Accession: NM_000686, NP_000677

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones