CYP11B1 anticorps (C-Term)

N° du produit ABIN2788349

Détail du produit anti-CYP11B1 anticorps

Antigène: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Épitope: C-Term

Reactivité: Humain, Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP11B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ARNPNVQQAL RQESLAAAAS ISEHPQKATT ELPLLRAALK ETLRLYPVGL

Homologie: Human: 100%, Pig: 79%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CYP11B1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP11B1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 503 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP11B1

Antigène: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Autre désignation: CYP11B1 (CYP11B1 Produits)

Synonymes: anticorps CPN1, anticorps CYP11B, anticorps FHI, anticorps P450C11, anticorps AA389061, anticorps Cyp11b, anticorps Cyp11b-1, anticorps Cp11ba, anticorps RATCP11BA, anticorps P450c11, anticorps cytochrome P450, family 11, subfamily B, polypeptide 1, anticorps cytochrome P450 family 11 subfamily B member 1, anticorps cytochrome P450, family 11, subfamily b, polypeptide 1, anticorps cytochrome P450, subfamily XI B, polypeptide 1, anticorps CYP11B1, anticorps Cyp11b1

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: CPN1, CYP11B, DKFZp686B05283, FHI, FLJ36771, P450C11
Protein Interaction Partner: CYP11B2,
Protein Size: 503

Poids moléculaire: 55 kDa

ID gène: 1584

NCBI Accession: NM_000497, NP_000488

UniProt: P15538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis