CYP21A2 anticorps (C-Term)

N° du produit ABIN2788351

Détail du produit anti-CYP21A2 anticorps

Antigène: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP21A2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IQQRLQEELD HELGPGASSS RVPYKDRARL PLLNATIAEV LRLRPVVPLA

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 80%, Human: 100%, Pig: 92%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CYP21A2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP21A2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 495 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP21A2

Antigène: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Autre désignation: CYP21A2 (CYP21A2 Produits)

Synonymes: anticorps CA21H, anticorps CAH1, anticorps CPS1, anticorps CYP21, anticorps CYP21B, anticorps P450c21B, anticorps 21-OH, anticorps 21OH, anticorps 21OHA, anticorps 21OHB, anticorps CYP21OH-A, anticorps Cyp21, anticorps Cyp21-ps1, anticorps Cyp21B, anticorps Cyp21a2-ps, anticorps Cyp21a2ps, anticorps Oh21-1, anticorps Oh21-2, anticorps CYP21A, anticorps 21-OHase, anticorps cytochrome P450 family 21 subfamily A member 2, anticorps cytochrome P450, family 21, subfamily a, polypeptide 1, anticorps cytochrome P450c21, anticorps cytochrome P450, family 21, subfamily A, polypepide 2, anticorps cytochrome P450, family 21, subfamily A, polypeptide 2, anticorps steroid 21-hydroxylase-like, anticorps CYP21A2, anticorps Cyp21a1, anticorps LOC101094596

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene, gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CA21H, CAH1, CPS1, CYP21, CYP21B, MGC150536, MGC150537, P450c21B
Protein Size: 495

Poids moléculaire: 56 kDa

ID gène: 1589

NCBI Accession: NM_000500, NP_000491

UniProt: Q16874

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process