GADD45A anticorps (C-Term)

N° du produit ABIN2788360

Détail du produit anti-GADD45A anticorps

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45A est non-conjugé

Application: Western Blotting (WB)

Séquence: LRVSNPGRLA ELLLLETDAG PAASEGAEQP PDLHCVLVTN PHSSQWKDPA

Homologie: Cow: 100%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GADD45A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GADD45A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 165 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GADD45A

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Autre désignation: GADD45A (GADD45A Produits)

Synonymes: anticorps MGC53491, anticorps zgc:91795, anticorps gadd45a, anticorps GADD45A, anticorps ddit1, anticorps gadd45, anticorps GADD45, anticorps AA545191, anticorps Ddit1, anticorps DDIT1, anticorps Gadd45, anticorps growth arrest and DNA damage inducible alpha L homeolog, anticorps growth arrest and DNA-damage-inducible, alpha, b, anticorps growth arrest and DNA damage inducible alpha, anticorps growth arrest and DNA damage-inducible protein 45, anticorps growth arrest and DNA-damage-inducible 45 alpha, anticorps growth arrest and DNA-damage-inducible, alpha, anticorps gadd45a.L, anticorps gadd45ab, anticorps GADD45A, anticorps gadd45a, anticorps GADD45, anticorps Gadd45a

Sujet: GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of GADD45A gene is mediated by both p53-dependent and -independent mechanisms.
Alias Symbols: DDIT1, GADD45
Protein Interaction Partner: ING4, UBC, AURKA, STAT3, PCNA, MTOR, CDK1, APEX1, DCTN2, RPS7, MDM2, MAPK1, TIAL1, HNRNPA0, SH3GLB1, PTPRK, PSMC3, NUCB2, CDK11A, ASCC2, FAS, CCNB1, DNMT1, JMJD1C, UBR1, SYNE4, MIDN, IGSF21, FBN3, FAM83D, MICAL1, SPTBN4, NRBP1, DNAJC13, ZHX1, C14orf1, ADA
Protein Size: 165

Poids moléculaire: 18 kDa

ID gène: 1647

NCBI Accession: NM_001924, NP_001915

UniProt: P24522

Pathways: Signalisation p53, Cycle Cellulaire