MUS81 anticorps (C-Term)
Aperçu rapide pour MUS81 anticorps (C-Term) (ABIN2788792)
Antigène
Voir toutes MUS81 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- GETRGGGHRP ELLRELQRLH VTHTVRKLHV GDFVWVAQET NPRDPANPGE
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Homologie
- Cow: 79%, Dog: 86%, Human: 100%, Mouse: 79%, Pig: 83%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against MUS81. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 551 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MUS81 (MUS81 Endonuclease Homolog (MUS81))
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Autre désignation
- MUS81
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Sujet
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MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
Alias Symbols: FLJ21012, FLJ44872, SLX3
Protein Interaction Partner: SLX4, vpr, EME1, PLK1, FBXL5, SLX1A, WEE1, EME2, SUMO2, SLX1B, MUS81, CHEK2, TERT, TERF2,
Protein Size: 551 -
Poids moléculaire
- 61 kDa
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ID gène
- 80198
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NCBI Accession
- NM_025128, NP_079404
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UniProt
- Q96NY9
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Pathways
- Réparation de l'ADN
Antigène
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