AKR1C3 anticorps (N-Term)

N° du produit ABIN2788802

Détail du produit anti-AKR1C3 anticorps

Antigène: AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))

Épitope: N-Term

Reactivité: Humain, Lapin, Rat, Souris, Boeuf (Vache), Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PALENSLKKA QLDYVDLYLI HSPMSLKPGE ELSPTDENGK VIFDIVDLCT

Homologie: Cow: 85%, Guinea Pig: 85%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 86%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against AKR1C3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 323 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1C3

Antigène: AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))

Autre désignation: AKR1C3 (AKR1C3 Produits)

Synonymes: anticorps AKR1C3, anticorps PGFS, anticorps MGC134333, anticorps DD3, anticorps DDX, anticorps HA1753, anticorps HAKRB, anticorps HAKRe, anticorps HSD17B5, anticorps hluPGFS, anticorps Akr1c18, anticorps aldo-keto reductase family 1, member C3 L homeolog, anticorps aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), anticorps aldo-keto reductase family 1 member C2, anticorps aldo-keto reductase family 1 member C3, anticorps aldo-keto reductase family 1, member C3, anticorps akr1c3.L, anticorps AKR1C3, anticorps LOC722496, anticorps Akr1c3

Sujet: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS
Protein Interaction Partner: UBC, LRIF1, ZHX1, UBE2W, ACIN1, MAGEA11,
Protein Size: 323

Poids moléculaire: 36 kDa

ID gène: 8644

NCBI Accession: NM_003739, NP_003730

UniProt: P42330

Pathways: Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus