IRAK4 anticorps (C-Term)

N° du produit ABIN2788803

Détail du produit anti-IRAK4 anticorps

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Épitope: C-Term

Reactivité: Humain, Rat, Boeuf (Vache), Cheval, Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK4 est non-conjugé

Application: Western Blotting (WB)

Séquence: TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS

Homologie: Cow: 77%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rat: 91%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against IRAK4. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 336 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IRAK4

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Autre désignation: IRAK4 (IRAK4 Produits)

Synonymes: anticorps zgc:55553, anticorps IRAK4, anticorps ipd1, anticorps irak-4, anticorps ny-ran-64, anticorps ny-ren-64, anticorps ren64, anticorps irak4, anticorps IPD1, anticorps IRAK-4, anticorps NY-REN-64, anticorps REN64, anticorps 8430405M07Rik, anticorps 9330209D03Rik, anticorps interleukin 1 receptor associated kinase 4, anticorps interleukin-1 receptor-associated kinase 4, anticorps IRAK4, anticorps irak4, anticorps Irak4

Sujet: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4
Protein Interaction Partner: MYD88, IRAK1, IKBKG, SASH1, ARNT, TNFRSF13B, IL1RL1, TRAF6, PELI1, PELI2, IL1R1, MBP, HIST1H1A, HIST1H1T, HIST1H1B, HIST1H1E, HIST1H1D, HIST1H1C, EIF4EBP1, TIRAP, IRAK3, IRAK2, TLR4, TICAM2, TBPL1, PELI3, UBC,
Protein Size: 336

Poids moléculaire: 36 kDa

ID gène: 51135

NCBI Accession: NM_001145256, NP_001138728

Pathways: Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades