GPER anticorps (C-Term)

N° du produit ABIN2789078

Cet anticorps anti-GPER Polyclonal Lapin (ABIN2789078) détecte spécifiquement GPER dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye et Cheval.

Aperçu rapide pour GPER anticorps (C-Term) (ABIN2789078)

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPER est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GPER anticorps

Épitope: C-Term

Fonction: GPER Antibody - C-terminal region

Séquence: SFLGETFRDK LRLYIEQKTN LPALNRFCHA ALKAVIPDST EQSDVRFSSA

Homologie: Dog: 100%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GPER. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62243-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPER

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Autre désignation: GPER

Sujet:

Background Information: This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

Gene Name: G protein-coupled estrogen receptor 1

Alternative Symbols: mER, CEPR, GPER, DRY12, FEG-1, GPR30, LERGU, LyGPR, CMKRL2, LERGU2, GPCR-Br

Protein Name: G-protein coupled estrogen receptor 1

Poids moléculaire: 42kDa

ID gène: 2852

NCBI Accession: NP_001091671

UniProt: Q99527

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process