GPER anticorps (C-Term)

N° du produit ABIN2789079

Détail du produit anti-GPER anticorps

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPER est non-conjugé

Application: Western Blotting (WB)

Séquence: NVFISVHLLQ RTQPGAAPCK QSFRHAHPLT GHIVNLAAFS NSCLNPLIYS

Homologie: Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 100%, Yeast: 83%

Attributs du produit: This is a rabbit polyclonal antibody against GPER. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 375 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPER

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Autre désignation: GPER (GPER Produits)

Synonymes: anticorps CEPR, anticorps CMKRL2, anticorps DRY12, anticorps FEG-1, anticorps GPCR-Br, anticorps GPER, anticorps GPR30, anticorps LERGU, anticorps LERGU2, anticorps LyGPR, anticorps 6330420K13Rik, anticorps Ceprl, anticorps Gper, anticorps Gpr30, anticorps GPR41, anticorps GPCR30, anticorps G protein-coupled estrogen receptor 1, anticorps GPER1, anticorps GPER, anticorps Gper1

Sujet: This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Alias Symbols: CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPR30, LERGU, LERGU2, LyGPR, MGC99678, GPER
Protein Interaction Partner: UBC,
Protein Size: 375

Poids moléculaire: 42 kDa

ID gène: 2852

NCBI Accession: NM_001505, NP_001496

UniProt: Q99527

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process