BMP4 anticorps (N-Term)

N° du produit ABIN2789355

Cet anticorps Lapin Polyclonal détecte spécifiquement BMP4 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Lapin, Boeuf (Vache), Mouton, Chien, Chévre, Cobaye et Cheval.

Aperçu rapide pour BMP4 anticorps (N-Term) (ABIN2789355)

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Mouton, Chien, Chévre, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BMP4 anticorps

Épitope: N-Term

Séquence: HASLIPETGK KKVAEIQGHA GGRRSGQSHE LLRDFEATLL QMFGLRRRPQ

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BMP4. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 408 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BMP4

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Autre désignation: BMP4

Sujet: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Alias Symbols: BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Protein Interaction Partner: BMPR2, ZFYVE9, UBC, BGN, GREM2, BMPER, SOSTDC1, CHRDL2, STAP2, BMPR1B, NOG, BMP8B, HTRA1, BMPR1A, CHRDL1, BMP4, TWSG1, CHRD,
Protein Size: 408

Poids moléculaire: 45 kDa

ID gène: 652

NCBI Accession: NM_130850, NP_570911

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development