SCARB1 anticorps (N-Term)

N° du produit ABIN2789394

Cité dans 1 publication. Cet anticorps anti-SCARB1 Polyclonal Lapin (ABIN2789394) détecte spécifiquement SCARB1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye et Lapin.

Aperçu rapide pour SCARB1 anticorps (N-Term) (ABIN2789394)

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SCARB1 anticorps

Épitope: N-Term

Fonction: SCARB1 Antibody - N-terminal region

Séquence: LEYRTFQFQP SKSHGSESDY IVMPNILVLG AAVMMENKPM TLKLIMTLAF

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SCARB1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63158-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SCARB1 (ABIN2789394)

Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." dans: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

Détails sur SCARB1

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Autre désignation: SCARB1

Sujet:

Background Information: The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Scavenger receptor class B, member 1

Alternative Symbols: CLA1, SRB1, CLA-1, SR-BI, CD36L1, HDLQTL6

Protein Name: Scavenger receptor class B member 1 Ensembl ENSP00000343795

Poids moléculaire: 56kDa

ID gène: 949

NCBI Accession: NP_001076428

UniProt: F8W8N0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome