ARTN anticorps (Middle Region)

N° du produit ABIN2789666

Détail du produit anti-ARTN anticorps

Antigène: ARTN (Artemin (ARTN))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARTN est non-conjugé

Application: Western Blotting (WB)

Séquence: RTARWCSGRA RRPPPQPSRP APPPPAPPSA LPRGGRAARA GGPGSRARAA

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ARTN. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 228 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ARTN

Antigène: ARTN (Artemin (ARTN))

Autre désignation: ARTN (ARTN Produits)

Synonymes: anticorps ARTN, anticorps ENOVIN, anticorps EVN, anticorps NBN, anticorps neublastin, anticorps artemin, anticorps ARTN, anticorps Artn

Sujet: The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ENOVIN, EVN, NBN
Protein Interaction Partner: GFRA3, ARTN,
Protein Size: 228

Poids moléculaire: 19 kDa

ID gène: 9048

NCBI Accession: NM_057090, NP_476431