NCK1 anticorps (N-Term)

N° du produit ABIN2789859

Détail du produit anti-NCK1 anticorps

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCK1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PSNYVERKNS ARKASIVKNL KDTLGIGKVK RKPSVPDSAS PADDSFVDPG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NCK1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 377 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NCK1

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Autre désignation: NCK1 (NCK1 Produits)

Synonymes: anticorps NCK, anticorps NCKalpha, anticorps nck-1, anticorps NCK1, anticorps 6330586M15Rik, anticorps D230010O13Rik, anticorps Nck, anticorps Nck-1, anticorps Nck1, anticorps nck, anticorps nck1-a, anticorps nck1-b, anticorps nckalpha, anticorps NCK adaptor protein 1, anticorps non-catalytic region of tyrosine kinase adaptor protein 1, anticorps NCK adaptor protein 1b, anticorps NCK adaptor protein 1 L homeolog, anticorps NCK1, anticorps Nck1, anticorps nck1b, anticorps nck1.L

Sujet: The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Alias Symbols: MGC12668, NCK, NCKalpha, nck-1
Protein Interaction Partner: UBC, CBL, SYNPO, WAS, Dok1, HSPA5, Mbp, SHANK3, KIAA1522, Caskin1, LPHN2, ADAM15, TUBA1A, ERBB3, EGFR, PHC2, FGFR1, MAP4K1, BCAR1, nef, ABI1, PAK1, DNM1, ABL1, TNK2, FASLG, UBASH3B, SYK, PIK3R1, LCP2, INPP5D, GRB2, KHDRBS1, UBA52, RASA1, NCKAP5, TNIK, BRK
Protein Size: 377

Poids moléculaire: 42 kDa

ID gène: 4690

NCBI Accession: NM_006153, NP_006144

UniProt: P16333

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals