CTDP1 anticorps (C-Term)

N° du produit ABIN2790245

Détail du produit anti-CTDP1 anticorps

Antigène: CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))

Épitope: C-Term

Reactivité: Humain, Souris, Chien, Cheval, Porc, Lapin, Rat, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTDP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: AHAPDKEPEL GGQEEGERDG LCGLGNGCAD RKEAETESQN SELSGVTAGE

Homologie: Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CTDP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTDP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 867 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CTDP1

Antigène: CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))

Autre désignation: CTDP1 (CTDP1 Produits)

Synonymes: anticorps CTDP1, anticorps CCFDN, anticorps FCP1, anticorps 4930563P03Rik, anticorps AW553592, anticorps CTD phosphatase subunit 1, anticorps CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1, anticorps RNA polymerase II subunit A C-terminal domain phosphatase, anticorps CTD phosphatase Fcp1, anticorps Ctdp1, anticorps CTDP1, anticorps ctdp1, anticorps ANI_1_2668024, anticorps AOR_1_1228154, anticorps CpipJ_CPIJ004583, anticorps PTRG_11566, anticorps SJAG_01286, anticorps MCYG_05528, anticorps VDBG_09811

Sujet: This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CCFDN, FCP1
Protein Interaction Partner: UBC, CDK9, UPP1, PPP2CA, PPP1CA, POLR2A, POLR2C, GRK5, ELP2, ELP3, SUMO2, PRKDC, CDK8, CDK7, INTS8, MED15, MED4, INTS6, INTS1, INTS7, MED16, MED6, MED24, MED7, MED26, MED17, MED23, MED14, MED1, MED8, MED25, INTS3, POLR2J, ERH, POLR2B, STK38, PRMT5, HIST1H
Protein Size: 867

Poids moléculaire: 93 kDa

ID gène: 9150

NCBI Accession: NM_048368, NP_430255

UniProt: Q9Y5B0