FLIP anticorps (Middle Region)
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- Antigène Voir toutes FLIP (CFLAR) Anticorps
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FLIP est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LNPEGGKSGK APRRRAASMD SSSKLLRGRS KAPKKKPSVL PAPPEGATPT
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CFLAR. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CFLAR
- Top Product
- Discover our top product CFLAR Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 480 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Autre désignation
- CFLAR (CFLAR Produits)
- Synonymes
- anticorps Clarp1, anticorps cflar, anticorps CFLAR, anticorps FLIP, anticorps CASH, anticorps CASP8AP1, anticorps CLARP, anticorps Casper, anticorps FLAME, anticorps FLAME-1, anticorps FLAME1, anticorps I-FLICE, anticorps MRIT, anticorps c-FLIP, anticorps c-FLIPL, anticorps c-FLIPR, anticorps c-FLIPS, anticorps 2310024N18Rik, anticorps A430105C05Rik, anticorps Cash, anticorps ENSMUSG00000072980, anticorps Flip, anticorps Gm9845, anticorps c-Flip, anticorps CASP8 and FADD-like apoptosis regulator a, anticorps CASP8 and FADD like apoptosis regulator, anticorps CASP8 and FADD like apoptosis regulator S homeolog, anticorps CASP8 and FADD-like apoptosis regulator, anticorps cflara, anticorps CFLAR, anticorps cflar, anticorps cflar.S, anticorps Cflar
- Sujet
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CFLAR belongs to the peptidase C14A family. It is a apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. The protein acts as an inhibitor of TNFRSF6 mediated apoptosis. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. CFLAR lacks enzymatic (caspase) activity.
Alias Symbols: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLIP, I-FLICE, MRIT, USURPIN, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, FLAME1
Protein Interaction Partner: FADD, TRAF1, GSN, SPATS1, TNFSF10, RIPK1, RAF1, SMAD3, CASP8, HSP90AA1, STUB1, TNFRSF10A, TNFRSF10B, UBC, FASLG, ITCH, DAXX, CBLB, ATG3, XRCC6, Mib1, TP53, DEDD2, DEDD, RIPK2, IKBKB, MAP2K7, TRAF2, CASP10, CASP7, CASP6, MAP2K4, PSEN2, CASP2, CASP3, BCL2L1
Protein Size: 480 - Poids moléculaire
- 55 kDa
- ID gène
- 8837
- NCBI Accession
- NM_003879, NP_003870
- UniProt
- O15519
- Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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