HTR2A anticorps (N-Term)
Aperçu rapide pour HTR2A anticorps (N-Term) (ABIN2792273)
Antigène
Voir toutes HTR2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- DILCEENTSL SSTTNSLMQL NDDTRLYSND FNSGEANTSD AFNWTVDSEN
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Homologie
- Human: 100%, Mouse: 78%, Pig: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against HTR2A. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 471 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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Autre désignation
- HTR2A
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Sujet
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HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Alias Symbols: 5-HT2A, HTR2
Protein Interaction Partner: LYN, CBL, NDUFB10, ANKS1B, MRPL28, EIF3F, DLG4, PON2, NME3, GNAQ, PPP5C, MAP1A, RPS6KA3, NTRK3, JAK2, GNA11, GNAI1, GLUL,
Protein Size: 471 -
Poids moléculaire
- 52 kDa
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ID gène
- 3356
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NCBI Accession
- NM_000621, NP_000612
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UniProt
- P28223
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Pathways
- Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
Antigène
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