SMAD4 anticorps (pThr277)

N° du produit ABIN2794149

Cet anticorps anti-SMAD4 est un anticorps Lapin Polyclonal détectant SMAD4 dans IHC, IF et DB. Adapté pour Humain.

Aperçu rapide pour SMAD4 anticorps (pThr277) (ABIN2794149)

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD4 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Dot Blot (DB)

Détail du produit anti-SMAD4 anticorps

Épitope: pThr277

Fonction: Rabbit Anti-Human Phospho-SMAD4(T277) Antibody

Immunogène: This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.

Isotype: Ig Fraction

Information d'application

Indications d'application: Immunofluorescence, Dot Blot, Immunohistochemistry
Recommended Dilutions
IF: 1:10-50, DB: 1:500, IHC: 1:10-50Confocal immunofluorescent analysis of Phospho-SMAD4-T277 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur SMAD4

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation: SMAD4

Sujet:

Target Description: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Gene Symbol: SMAD4

Poids moléculaire: 60439 Da

ID gène: 4089

UniProt: Q13485

Pathways: Cycle Cellulaire, Chromatin Binding, Autophagy