Stanniocalcin 2 anticorps (C-Term)

N° du produit ABIN2798536

Cet anticorps Lapin Polyclonal détecte spécifiquement Stanniocalcin 2 dans WB et IHC. Il présente une réactivité envers Souris.

Aperçu rapide pour Stanniocalcin 2 anticorps (C-Term) (ABIN2798536)

Antigène: Stanniocalcin 2 (STC2)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stanniocalcin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Stanniocalcin 2 anticorps

Épitope: AA 273-302, C-Term

Fonction: Rabbit Anti-Mouse STC2 (C-term) Antibody

Immunogène: This STC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the C-terminal region of human STC2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50STC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur Stanniocalcin 2

Antigène: Stanniocalcin 2 (STC2)

Autre désignation: STC2

Sujet:

Target Description: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Gene Symbol: STC2

Poids moléculaire: 33249 Da

ID gène: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome