TLR2 anticorps (N-Term)

N° du produit ABIN2798860

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR2 dans WB, IHC et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour TLR2 anticorps (N-Term) (ABIN2798860)

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-TLR2 anticorps

Épitope: AA 212-242, N-Term

Fonction: Rabbit Anti-Human TLR2 (N-term) Antibody

Immunogène: This TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the N-terminal region of human TLR2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of hTLR2-C226 . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur TLR2

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Autre désignation: TLR2

Sujet:

Target Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Gene Symbol: TLR2

Poids moléculaire: 89838 Da

ID gène: 7097

UniProt: O60603

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades