CCDC39 anticorps (Alexa Fluor 594)

N° du produit ABIN2811218

Détail du produit anti-CCDC39 anticorps (Alexa Fluor 594)

Antigène: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC39 est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB)

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CCDC39

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CCDC39

Antigène: CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))

Autre désignation: CCDC39 (CCDC39 Produits)

Synonymes: anticorps 4921507O14Rik, anticorps AI447426, anticorps AI844750, anticorps D3Ertd789e, anticorps b2b1304Clo, anticorps b2b1735Clo, anticorps RGD1306277, anticorps CILD14, anticorps FAP59, anticorps coiled-coil domain containing 39, anticorps flagellar associated protein, anticorps Ccdc39, anticorps CCDC39, anticorps ccdc39, anticorps FAP59

Sujet:

Synonyms: CCD39_HUMAN, Ccdc39, Coiled-coil domain-containing protein 39.

Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

ID gène: 339829