HGD anticorps (AA 351-445) (Alexa Fluor 594)

N° du produit ABIN2814318

Détail du produit anti-HGD anticorps (Alexa Fluor 594)

Antigène: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Épitope: AA 351-445

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HGD est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HGD

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HGD

Antigène: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Autre désignation: HGD (HGD Produits)

Synonymes: anticorps CG4779, anticorps Dmel\\CG4779, anticorps PSPTO3551, anticorps DDBDRAFT_0185702, anticorps DDBDRAFT_0191461, anticorps DDB_0185702, anticorps DDB_0191461, anticorps Hgo, anticorps aku, anticorps hgo, anticorps AKU, anticorps HGO, anticorps homogentisate 1,2-dioxygenase, anticorps Homogentisate 1,2-dioxygenase, anticorps homogentisate 1, 2-dioxygenase, anticorps homogentisate 1,2-dioxygenase L homeolog, anticorps hgo, anticorps HGD, anticorps hmgA, anticorps Shewana3_2481, anticorps hgd, anticorps BC1002_0545, anticorps BC1003_0502, anticorps BC1001_0489, anticorps Sinme_2995, anticorps Sphch_0441, anticorps Hgd, anticorps hgd.L

Sujet:

Synonyms: 2-dioxygenase, AKU, FLJ94126, hgd, HGD_HUMAN, HGO, Homogentisate 1 2 dioxygenase, Homogentisate 1, Homogentisate oxidase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.

Background: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyze the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterized by urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

ID gène: 3081