Presenilin 1 anticorps (N-Term)
Aperçu rapide pour Presenilin 1 anticorps (N-Term) (ABIN285063)
Antigène
Voir toutes Presenilin 1 (PSEN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 14-33, N-Term
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Immunogène
- Presenilin 1 antibody was raised in goat using a synthetic peptide corresponding to amino acid residues 14-33 of the N-terminus of the alzheimer's disease presenilin-1 as the immunogen.
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Isotype
- IgG
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Indications d'application
- Optimal conditions should be determined byt he investigator.
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Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, with 0.05 % NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Presenilin 1 (PSEN1)
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Autre désignation
- Presenilin 1
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Sujet
- Presenilins are a family of related multi-pass transmembrane proteins that function as a part of the gamma-secretase protease complex. Vertebrates have two presenilin genes, called PSEN1 (located on chromosome 14 in humans) that encodes presenilin 1 (PS-1) and PSEN2 (on chromosome 1 in humans) that codes for presenilin 2 (PS-2).
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Pathways
- Signalisation Notch, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Antigène
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