WT1 anticorps (Center)
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- Antigène Voir toutes WT1 Anticorps
- WT1 (Wilms Tumor 1 (WT1))
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Épitope
- Center
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WT1 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Attributs du produit
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Rabbit Polyclonal antibody to Wilms Tumor 1 (Wilms tumor 1)
Wilms Tumor 1 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human Wilms Tumor 1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product WT1 Anticorps primaire
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- Indications d'application
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*
- Commentaires
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Positive Control: Mouse testis, Rat testis
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.11 mg/mL
- Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- WT1 (Wilms Tumor 1 (WT1))
- Autre désignation
- Wilms Tumor 1 (WT1 Produits)
- Synonymes
- anticorps AWT1, anticorps EWS-WT1, anticorps GUD, anticorps NPHS4, anticorps WAGR, anticorps WIT-2, anticorps WT33, anticorps CWT1, anticorps WT1, anticorps XWT1a, anticorps wt-1, anticorps wt1, anticorps xWT1, anticorps WT-1, anticorps gud, anticorps wagr, anticorps wt33, anticorps xwt1, anticorps wit-2, anticorps si:ch211-160j6.3, anticorps zgc:152697, anticorps D630046I19Rik, anticorps Wt-1, anticorps XWT1b, anticorps XeWT1, anticorps Wilms tumor 1, anticorps Wilms tumor 1 S homeolog, anticorps wilms tumor 1b, anticorps Wilms tumor protein, anticorps Wilms tumor 1 homolog, anticorps Wilms tumor 1 L homeolog, anticorps WT1, anticorps wt1.S, anticorps wt1, anticorps wt1b, anticorps Wt1, anticorps wt1.L
- Sujet
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This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
Cellular Localization: Nucleus - Poids moléculaire
- 49 kDa
- ID gène
- 7490
- Pathways
- Tube Formation
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