RAD51 Homolog B anticorps (Center)
Aperçu rapide pour RAD51 Homolog B anticorps (Center) (ABIN2854538)
Antigène
Voir toutes RAD51 Homolog B (Rad51B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée
- Souris, Boeuf (Vache)
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Réactivité croisée (Details)
- Mouse (86 %), Bovine (91 %)
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Attributs du produit
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Rabbit polyclonal antibody to RAD51L1 (RAD51-like 1 (S. cerevisiae))
RAD51B antibody [N1C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human RAD51B. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Commentaires
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Positive Control: Raji
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RAD51 Homolog B (Rad51B)
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Autre désignation
- RAD51L1
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Sujet
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The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Cellular Localization: Nucleus -
Poids moléculaire
- 42 kDa
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ID gène
- 5890
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Pathways
- Réparation de l'ADN
Antigène
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