NR2F6 anticorps (C-Term)
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- Antigène Voir toutes NR2F6 Anticorps
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR2F6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP)
- Réactivité croisée
- Humain, Souris
- Attributs du produit
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Rabbit Polyclonal antibody to NR2F6 (nuclear receptor subfamily 2, group F, member 6)
NR2F6 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NR2F6. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product NR2F6 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
- Autre désignation
- nuclear receptor subfamily 2 group F member 6 (NR2F6 Produits)
- Synonymes
- anticorps EAR-2, anticorps EAR2, anticorps ERBAL2, anticorps AV090102, anticorps COUP-TF3, anticorps Erbal2, anticorps COUP(II), anticorps NR2F6, anticorps couptf2, anticorps fc94g11, anticorps wu:fc94g11, anticorps zgc:77259, anticorps ear-2, anticorps ear2, anticorps erbal2, anticorps nr2f6l, anticorps wu:fc72d04, anticorps zgc:77260, anticorps nuclear receptor subfamily 2 group F member 6, anticorps nuclear receptor subfamily 2, group F, member 6, anticorps nuclear receptor subfamily 2, group F, member 6a, anticorps nuclear receptor subfamily 2 group F member 6 L homeolog, anticorps nuclear receptor subfamily 2, group F, member 6b, anticorps NR2F6, anticorps Nr2f6, anticorps nr2f6a, anticorps nr2f6.L, anticorps nr2f6, anticorps nr2f6b
- Sujet
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Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock, is required early in the development of the locus coeruleus (LC).
Cellular Localization: Nucleus - Poids moléculaire
- 43 kDa
- ID gène
- 2063
- UniProt
- P10588
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism
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