EDNRB anticorps (N-Term)

N° du produit ABIN2854727

Détail du produit anti-EDNRB anticorps

Antigène: EDNRB (Endothelin Receptor Type B (EDNRB))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDNRB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to ETBR (endothelin receptor type B)
ETBR antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Endothelin B Receptor. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431 , H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur EDNRB

Antigène: EDNRB (Endothelin Receptor Type B (EDNRB))

Autre désignation: endothelin receptor type B (EDNRB Produits)

Synonymes: anticorps ABCDS, anticorps ET-B, anticorps ET-BR, anticorps ETB, anticorps ETBR, anticorps ETRB, anticorps HSCR, anticorps HSCR2, anticorps WS4A, anticorps Ednra, anticorps Etb, anticorps ETR-b, anticorps ETb, anticorps Sox10m1, anticorps EDNRB, anticorps abcds, anticorps etb, anticorps etrb, anticorps hscr, anticorps hscr2, anticorps endothelin receptor type B, anticorps EDNRB, anticorps Ednrb, anticorps ednrb

Sujet: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct.

Cellular Localization: Cell membrane

Poids moléculaire: 50 kDa

ID gène: 1910

UniProt: P24530

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process